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TopBac® consists in a proprietary patented expression cassette composed by several genetic regulatory elements working in cascade. When incorporated into the genome of a baculovirus vector, improves to unprecedented levels the productivity and quality of recombinant proteins produced by host cells.

Apoptosis inhibition (Sf IAP)

TopBac® is fully compatible with the most common baculovirus vector-based production technologies, and consistently provides to the system up to 400% increase in production yields in insect cells above current industry standards. Additionally, TopBac® also improves product quality by reducing foreign protein proteolysis.
TopBac® has been tested for the production of a variety of proteins in insect cells and insects (CrisBioTM technology), increasing productivities in both platforms.
Download Top-Bac® flyer
Download TopBac® flyer